The nucleotide sequence of human acylamino acid-releasing enzyme.
نویسندگان
چکیده
The nucleotide sequence of a cDNA coding for the human acylamino acid-releasing enzyme (AARE, also known as acylpeptide hydrolase) [EC 3.4.19.1] subunit has been determined. The amino acid sequence of human AARE subunit deduced from its cDNA nucleotide sequence showed a high degree of identity (91.5%) with both the corresponding proteins from the pig and the rat. The AARE cDNA shows 99.2% identity with a 3.3 kb cDNA transcribed from a locus (DNF15S2) on the short arm of human chromosome 3, whose deletion is associated with small cell lung cancer, taking into consideration that the sequence of the 3.3-kb cDNA previously reported was caused by misreading.
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ورودعنوان ژورنال:
- DNA research : an international journal for rapid publication of reports on genes and genomes
دوره 3 1 شماره
صفحات -
تاریخ انتشار 1996